Treatment with fluconazole should be initiated by a physician experienced in the management
of invasive fungal infections. The dose is dependent on the type and severity of the infection.
The treatment of infections requiring multiple-dosing must be continued until clinical
parameters or laboratory results show that the active infection has declined. An insufficient
treatment period may lead to recurrence of the active infection.
Fluconazole is also available for oral therapy. The patient should be switched from dosing by
the intravenous route to dosing by the oral route as soon as possible. It is not necessary to
change the daily dose of fluconazole when changing the route of administration from
intravenous to oral.